Saturday, February 7, 2009

Cramping on dialysis

When does someone cramp on dialysis?

Based on my experience, I have seen two kinds of situations when someone cramps during dialysis:

- When the rate of fluid removal is too high
- When too much fluid is removed

What's the difference between the two, you might wonder? There is. Let me explain.

My dry weight is 79 kgs. Dry weight for the uninitiated, is the body weight when there is no excess fluid in the body. Why might there be excess fluid in the body? For the horribly uninitiated, when the kidneys don't work, fluid builds up in the body because the kidneys do not remove it.

So, my dry weight is 79 kgs. Let's say I put on about 3 kgs as a result of drinking too much water. Now the goal of dialysis usually is to come back to your dry weight. So, ideally I must remove 3 liters of water (because a liter of water weighs about a kilogram) to come back to my dry weight.

If I dialyze for 4 hours, I must remove water from my body at the rate of 750 ml/hour which is too high. Studies have shown that when water is removed from the body at a rate greater than about 400 ml/hour, it is too fast. Cramps can happen.

Another possibility is that too much water is removed, even if the rate of removal is 400 ml/hour or less. For example, let's say I did a 9 hour session and tried to remove 3.5 liters of water during the 9 hour treatment. Even though the rate of fluid removal is less than 400 ml/hour, cramps can occur because I will be below my dry weight towards the end of treatment. Basically I am squeezing my muscles of the water needed for them to function. This results in cramps.

That is why proper monitoring of the dry weight is very important. Unfortunately there is no accurate method of determining the dry weight. We have to use indicators like general feeling of well being and the blood pressure to guess the dry weight.

Who said being on dialysis is fun?!

6 comments:

Dave said...

Good post, Kamal. As one who suffers leg cramps about every 3rd dialysis run, anything that gives me insite to the cause is valuable to me. My downfall is root beer. I love it! But if I drink more than half a can a day, I pay for it during dialysis. So my kitchen sink drinks as much of it as I do.

Kamal Shah said...

Hi Dave,

You can have a little extra fluid during the first hour of dialysis. Have you considered daily home hemo?

I visited your blog - really cool template you have there!

Kamal

Mark Lee, M.D. nephrology said...

Also using low K+ bath (esp. 1 K+ bath) can cause cramping towards the end of hemodialysis due to transient hypokalemia.

Kamal D Shah said...

Thanks for the information Dr. Lee!

Rooster Inn Primitives said...

Hello

Came acrossed your blog looking for answeres for my husband..He goes to dialysis 3 times a week and latley he has been cramping really bad. Mostly his hands and his neck to the point he has a hard time breathing. He has told them about it but they said they don't understand why he cramps. I will read some more of your blog and maybe get some answeres.

thanks

Kamal D Shah said...

How much fluid weight does he typically gain between treatments? Maybe, they need to remove less? Maybe his dry weight has increased?

Just some initial thoughts.

Kamal